Symptomatic treatment of OA & RA; relief of signs & symptoms of ankylosing spondylitis; management of acute pain; treatment of primary dysmenorrhea; acute & chronic low back pain.
AdultSymptomatic treatment of OA, ankylosing spondylitis 200 mg as single dose or 100 mg bid. Symptomatic treatment of RA 100 or 200 mg bid. Management of acute pain Initially 400 mg followed by 200 mg on the 1st day & 200 mg bid or 400 mg once daily subsequently. Treatment of primary dysmenorrhea Initially 400 mg followed by 200 mg on the 1st day & 200 mg bid subsequently.
May be taken with or without food: Dose of OA/RA may be given w/ or w/o meals.
Contraindications
Hypersensitivity to celecoxib or sulfonamides. Patients who have experienced asthma, urticaria or allergic-type reactions after taking aspirin or NSAIDs including COX-2 inhibitors. Treatment of peri-operative pain in the setting of CABG.
Patients w/ ischemic heart disease & those at risk of heart disease, HTN, hyperlipidemia, diabetes, smoking; peripheral arterial disease. Risk of CV, GI, renal & hepatic effects; fluid retention & edema; anaphylactoid & serious skin reactions. Concomitant use w/ warfarin or similar agents; non-aspirin NSAID. May diminish utility of diagnostic signs eg, fever in detecting infections. Not a substitute for aspirin in the prophylactic treatment of CV disease. Pregnancy & lactation.
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